This manual is designed to contain the Department of Science and Technology - Biosafety Committee (DOST-BC) guidelines and procedures to serve its primary purpose. It is intended for scientists, researchers, and private and public institutions conducting experiments on Genetically Modified Organisms (GMOs) under the aforementioned conditions.

Specifically, the DOST-BC guidelines provides policies and procedures for application and monitoring of
contained use and confined tests of GMOs. Hence, this manual aims to facilitate the process of ensuring that the best available science is adopted in assessing proposals to minimize risks posed by GMOs to the
environment, animal and human health.

This manual further provides the specific functions of DOST-BC as a regulatory body, the roles and
responsibilities of the Institutional Biosafety Committee (IBC) as a regulator of the institution undertaking GM experiments, the proponents, and other external experts and consultants. It also includes the required level of containment for any particular activity, packaging, transport and  handling of regulated materials and basic instructions,monitoring, and appropriate measures in case of incidents resulting from the use of GMOs. Moreover, it features prescribed forms  for the preparation of project proposals, IBC assessments, and submission of reports.